La Fondation Universitaire peut accorder des subsides pour promouvoir la publication d'articles scientifiques dans des revues internationales.
Ce qui suit est une liste d'articles scientifiques qui ont été subventionnés par la Fondation Universitaire. Les articles sont triés par année de publication et par titre.
A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels
Philippaert, K. et al. (2018) A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels. SLAS Discovery.
TRPM5 functions as a calcium-activated monovalent cation-selective ion channel and is expressed in a variety of cell types. Dysfunction of this type of channel has been recently implied in cardiac arrhythmias, diabetes, and other pathologies. Therefore, a growing interest has emerged to develop the pharmacology of these ion channels. We optimized a screening assay based on the thallium flux through the TRPM5 channel and a fluorescent thallium dye as a probe for channel activity.
Klaas M. et al (2018) Acute Effect of Noradrenergic Modulation on Motor Output Adjustment in Men. Medicine & Science in Sports & Exercise.
Piers, R. et al (2018) Advance care planning in dementia: recommendations for healthcare professionals. BMC Palliative Care, 2018, 17:88, https://doi.org/10.1186/s12904-018-0332-2
Background: Advance care planning (ACP) is a continuous, dynamic process of reflection and dialogue between an individual, those close to them and their healthcare professionals, concerning the individual’s preferences and values concerning future treatment and care, including end-of-life care.
Assessment of medication adherence and responsible use of isotretinoin and contraception through Belgian community pharmacies by using pharmacy refill data
Biset, N. et al. (2018) Assessment of medication adherence and responsible use of isotretinoin and contraception through Belgian community pharmacies by using pharmacy refill data. Patient Preference and Adherence 12 153–161.
Purpose: The aims of the study were to evaluate medication adherence and the influencing factors for isotretinoin and contraception (oral, patches, and rings) and to evaluate the concomitant use of contraception and isotretinoin.
Extracellular S100A9 Protein in Bone Marrow Supports Multiple Myeloma Survival by Stimulating Angiogenesis and Cytokine Secretion
De Veirman, K. et al. (2018) Extracellular S100A9 Protein in Bone Marrow Supports Multiple Myeloma Survival by Stimulating Angiogenesis and Cytokine Secretion. Cancer Immunol Res. 5(10), 839–46.
Gilissen, J. et al. How to achieve the desired outcomes of advance care planning in nursing homes: a theory of change BMC Geriatrics (2018, 18:47 DOI 10.1186/s12877-018-0723-5.
A. Woller & D. Gonze (2018) Modeling clock-related metabolic syndrome due to conflicting light and food cues, Scientific Reports 8:13641 | DOI:10.1038/s41598-018-31804-9.
Gonze, D. et al. (2018) Modeling-Based Investigation of the Effect of Noise in Cellular Systems, Frontiers in Molecular Biosciences, vol 5, April 2018.
Noise is pervasive in cellular biology and inevitably affects the dynamics of cellular processes.
Biological systems have developed regulatory mechanisms to ensure robustness with respect to noise or to take advantage of stochasticity. We review here, through a couple of selected examples, some insights on possible robustness factors and constructive roles of noise provided by computational modeling. In particular, we focus on
Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade
Dewaele, J. et al. (2018) Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade. OncoImmunology, vol. 7 no 3.
Prognosis of glioblastoma remains dismal, underscoring the need for novel therapies. Immunotherapy is generating promising results, but requires combination strategies to unlock its full potential. We investigated the immunomodulatory capacities of poly(I:C) on primary human glioblastoma cells and its combinatorial potential with programmed death ligand (PD-L) blockade. In our experiments, poly(I:C) stimulated expression of both PD-L1 and PD-L2 on glioblastoma cells, and a pro-inflammatory secretome, including type I interferons (IFN) and chemokines CXCL9, CXCL10, CCL4 and CCL5.
Student researchers’ perceived prerequisites for voluntary research collaboration in the context of Flemish and Chinese universities
Li S, Zhu C, Li S (2018) Student researchers’ perceived prerequisites for voluntary research collaboration in the context of Flemish and Chinese universities. PLoS ONE 13(5): e0197960. https://doi.org/10.1371/journal.pone.0197960
While numerous papers have illuminated the worthiness of research collaboration, relatively few have addressed its prerequisites. In our study, seven prerequisites for research collaboration were extracted from the existing literature, and 460 student researchers were surveyed for their perceptions of the prerequisites’ importance.
Calderon, C.B. et al. (2018) Task-Relevant Information Modulates Primary Motor Cortex Activity Before Movement Onset.Frontiers in Human Neuroscience,Volume 12, Article 93.
Temperature and water stress affect plant–pollinator interactions in Borago officinalis (Boraginaceae)
Descamps, C. et al. (2018) Temperature and water stress affect plant–pollinator interactions in Borago officinalis (Boraginaceae).Ecology and Evolution, vol. 8, 3443 –3456.
Climate change alters the abiotic constraints faced by plants, including increasing temperature and water stress. These changes may affect flower evelopment and production of flower rewards, thus altering plant–pollinator interactions. Here, we investigated the consequences of increased temperature and water stress on plant growth, floral biology, flower-reward production, and insect visitation of a widespread bee-visited species, Borago officin alis. Plants were grown for 5 weeks under three temperature regimes (21, 24, and 27°C) and two watering regimes (well-watered and water-stressed).
The Future of Freshwater Macrophytes in a Changing World: Dissolved Organic Carbon Quantity and Quality and Its Interactions With Macrophytes
Reitseman R.E. et al. (2018) The Future of Freshwater Macrophytes in a Changing World: Dissolved Organic Carbon Quantity and Quality and Its Interactions With Macrophytes. Frontiers in Plant Science, Functional Plant Ecology, May 2018.
The influence of soil properties and nutrients on conifer forest growth in Sweden, and the first steps in developing a nutrient availability metric
Van Sundert, K. et al. (2018) The influence of soil properties and nutrients on conifer forest growth in Sweden, and the first steps in developing a nutrient availability metric. Biogeosciences, 15, 3475–3496, 2018, https://doi.org/10.5194/bg-15-3475-2018.
The availability of nutrients is one of the factors that regulate terrestrial carbon cycling and modify ecosystem responses to environmental changes. Nonetheless, nutrient availability is often overlooked in climate–carbon cycle studies because it depends on the interplay of various soil factors that would ideally be comprised into metrics applicable at large spatial scales. Such metrics do not currently exist.
‘I am always crying on the inside’: a qualitative study on the implications of infertility on women’s lives in urban Gambia
Dierickx S. et al. ‘I am always crying on the inside’: a qualitative study on the implications of infertility on women’s lives in urban Gambia. Reproductive Health 15:151, https://doi.org/10.1186/s12978-018-0596-2