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Wat volgt is een lijst van wetenschappelijke artikelen die recent gesubsidieerd werden door de Universitaire Stichting. De artikelen zijn gesorteerd op jaar van uitgave en per titel.
Citizenship Pressure as a Predictor of Daily Enactment of Autonomous and Controlled Organizational Citizenship Behavior: Differential Spillover Effects on the Home Domain
Germeys, L. et al. (2019) Citizenship Pressure as a Predictor of Daily Enactment of Autonomous and Controlled Organizational Citizenship Behavior: Differential Spillover Effects on the Home Domain. Frontiers in Psychology https://doi.org/10.3389/fpsyg.2019.00395.
This study questions the exclusive discretionary nature of organizational citizenship behavior (OCB) by differentiating between autonomous OCB (performed spontaneously) and controlled OCB (performed in response to a request from others). We examined whether citizenship pressure evokes the performance of autonomous and controlled OCB, and whether both OCB types have different effects on employees’ experience of work-home conflict and work-home enrichment at the within- and between-person level of analysis.
Temperature preference of Nile tilapia (Oreochromis niloticus) juveniles induces spontaneous sex reversal
Nivelle R. et al. (2019) Temperature preference of Nile tilapia (Oreochromis niloticus) juveniles induces spontaneous sex reversal. PLoS ONE 14(2): e0212504. https://doi.org/10.1371/journal.pone.0212504
Nile tilapia (Oreochromis niloticus) is an African freshwater fish that displays a genetic sex determination system (XX|XY) where high temperatures (above 32°C to 36.5°C) induce masculinization. In Nile tilapia, the thermosensitive period was reported from 10 to 30 days post fertilization. In their natural environment, juveniles may encounter high temperatures that are above the optimal temperature for growth (27–30°C). The relevance of the thermal sex reversal mechanism in a natural context remains unclear.
Use and timing of referral to specialized palliative care services for people with cancer: A mortality follow-back study among treating physicians in Belgium
Vanbutsele, G. et al. (2019) Use and timing of referral to specialized palliative care services for people with cancer: A mortality follow-back study among treating physicians in Belgium. Plos One.
Referral to specialized palliative care services (SPCS) occurs often late in the illness trajectory but may differ across cancer types. We examined differences between cancer types in the use and timing of referral to specialized palliative care services (SPCS) and in the reasons for non-referral.
A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels
Philippaert, K. et al. (2018) A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels. SLAS Discovery.
TRPM5 functions as a calcium-activated monovalent cation-selective ion channel and is expressed in a variety of cell types. Dysfunction of this type of channel has been recently implied in cardiac arrhythmias, diabetes, and other pathologies. Therefore, a growing interest has emerged to develop the pharmacology of these ion channels. We optimized a screening assay based on the thallium flux through the TRPM5 channel and a fluorescent thallium dye as a probe for channel activity.
Klaas M. et al (2018) Acute Effect of Noradrenergic Modulation on Motor Output Adjustment in Men. Medicine & Science in Sports & Exercise.
Piers, R. et al (2018) Advance care planning in dementia: recommendations for healthcare professionals. BMC Palliative Care, 2018, 17:88, https://doi.org/10.1186/s12904-018-0332-2
Background: Advance care planning (ACP) is a continuous, dynamic process of reflection and dialogue between an individual, those close to them and their healthcare professionals, concerning the individual’s preferences and values concerning future treatment and care, including end-of-life care.
Assessing out-of-pocket expenditures for primary health care: how responsive is the Democratic Republic of Congo health system to providing financial risk protection?
Laokri, S. et al (2018) Assessing out-of-pocket expenditures for primary health care: how responsive is the Democratic Republic of Congo health system to providing financial risk protection? BMC Health Services Research.
Background: The goal of universal health coverage is challenging for chronically under-resourced health systems. Although household out-of-pocket payments are the most important source of health financing in low-income countries, relatively little is known about the drivers of primary health care expenditure and the predictability of the burden associated with high fee-for-service payments.
Assessment of medication adherence and responsible use of isotretinoin and contraception through Belgian community pharmacies by using pharmacy refill data
Biset, N. et al. (2018) Assessment of medication adherence and responsible use of isotretinoin and contraception through Belgian community pharmacies by using pharmacy refill data. Patient Preference and Adherence 12 153–161.
Purpose: The aims of the study were to evaluate medication adherence and the influencing factors for isotretinoin and contraception (oral, patches, and rings) and to evaluate the concomitant use of contraception and isotretinoin.
Exosomes play a role in multiple myeloma bone disease and tumor development by targeting osteoclasts and osteoblasts
Faict, S. et al. (2018) Exosomes play a role in multiple myeloma bone disease and tumor development by targeting osteoclasts and osteoblasts. Blood Cancer Journal 8:105
Progression of multiple myeloma (MM) is largely dependent on the bone marrow (BM) microenvironment wherein communication through different factors including extracellular vesicles takes place. This cross-talk not only leads to drug resistance but also to the development of osteolysis. Targeting vesicle secretion could therefore simultaneously ameliorate drug response and bone disease. In this paper, we examined the effects of MM exosomes on different aspects of osteolysis using the 5TGM1 murine model.
Extracellular S100A9 Protein in Bone Marrow Supports Multiple Myeloma Survival by Stimulating Angiogenesis and Cytokine Secretion
De Veirman, K. et al. (2018) Extracellular S100A9 Protein in Bone Marrow Supports Multiple Myeloma Survival by Stimulating Angiogenesis and Cytokine Secretion. Cancer Immunol Res. 5(10), 839–46.
Gilissen, J. et al. How to achieve the desired outcomes of advance care planning in nursing homes: a theory of change BMC Geriatrics (2018, 18:47 DOI 10.1186/s12877-018-0723-5.
Lelubre;, M. et al. (2018) Implementation study of an intermediate medication review in Belgian community pharmacies. Research in Social and Administrative Pharmacy.
Is the socioeconomic status of immigrant mothers in Brussels relevant to predict their risk of adverse pregnancy outcomes?
Sow, M. et al. (2018) Is the socioeconomic status of immigrant mothers in Brussels relevant to predict their risk of adverse pregnancy outcomes? BMC Pregnancy and Childbirth. 2018, 118:422.
Background: Understanding and tackling perinatal health inequities in industrialized countries requires analysing the socioeconomic determinants of adverse pregnancy outcomes among immigrant populations. Studies show that among certain migrant groups, education is not associated with adverse pregnancy outcomes. We aim to extend this analysis to further dimensions of socioeconomic status (SES) and to other settings.
A. Woller & D. Gonze (2018) Modeling clock-related metabolic syndrome due to conflicting light and food cues, Scientific Reports 8:13641 | DOI:10.1038/s41598-018-31804-9.
Gonze, D. et al. (2018) Modeling-Based Investigation of the Effect of Noise in Cellular Systems, Frontiers in Molecular Biosciences, vol 5, April 2018.
Noise is pervasive in cellular biology and inevitably affects the dynamics of cellular processes.
Biological systems have developed regulatory mechanisms to ensure robustness with respect to noise or to take advantage of stochasticity. We review here, through a couple of selected examples, some insights on possible robustness factors and constructive roles of noise provided by computational modeling. In particular, we focus on